NMN: The Future of Anti-Aging? A Deep Dive into Nicotinamide Mononucleotide

Introduction

Nicotinamide Mononucleotide (NMN) has emerged as one of the most talked-about supplements in the longevity community. As a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), NMN plays a critical role in cellular energy production and DNA repair.

Clinical Studies and Benefits

Recent research has highlighted several potential benefits of NMN supplementation:

1. Insulin Sensitivity: A 2021 study in Science found that NMN improved muscle insulin sensitivity in prediabetic women.
2. Aerobic Capacity: Research published in the Journal of the International Society of Sports Nutrition indicated improved aerobic performance in runners.
3. Longevity and NAD+ Boost: Human clinical trials have confirmed that NMN effectively raises NAD+ levels, which naturally decline with age.

Safety and Dosing

Human trials, including those at Keio University, have demonstrated that single doses up to 500mg are safe. Longer-term studies are ongoing to establish optimal chronic dosing protocols.

Conclusion

While more large-scale human trials are needed, NMN remains a promising compound for those looking to support cellular health and longevity. Always consult with a healthcare professional before starting new supplements.